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Gene Symbol SMARCD1
Synonyms BAF60A | CRACD1 | CSS11 | Rsc6p
Gene Description SMARCD1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, encodes a component of the SWI/SNF complex that facilitates chromatin remodeling by interacting with the glucocorticoid receptor and mediates antitumor activity by directly interacting with Tp53 (PMID: 19234488, PMID: 12917342, PMID: 18303029). SMARCD1 mutations have been identified in breast cancer (PMID: 22722201).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
6602 12 12q13.12 NM_003076 Tumor suppressor (PMID: 30606230)
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