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Gene Symbol SOX2
Synonyms ANOP3 | MCOPS3
Gene Description SOX2, SRY-box transcription factor 2, plays a significant role in the determination and reprogramming of cell fate via gene expression regulation, which often requires cofactors (PMID: 31477842). SOX2 amplification has been identified in multiple tumor types, including non-small cell lung cancer and glioblastoma (PMID: 22941189, PMID: 21518820, PMID: 25114775).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
6657 3 3q26.33 NM_003106 oncogene (PMID: 30606230)
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