Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol SRP54
Synonyms SCN8
Gene Description SRP54, signal recognition particle 54, is part of the ribonucleoprotein complex (PMID: 32277798) that regulates protein shuttling to the ER, and regulates secretion and membrane integration of nascent proteins, including death receptor 4, which mediates apoptosis (PMID: 15356269). Amplification of SRP54 has been identified in esophageal squamous cell carcinoma (PMID: 11550278).
Additional content available in CKB BOOST