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Gene Symbol | SSRP1 | ||||||||||
Synonyms | FACT | FACT80 | T160 | ||||||||||
Gene Description | SSRP1, structure specific recognition protein 1, is a histone chaperone and forms part of the facilitates chromatin transcription (FACT) complex to mediate DNA replication, DNA damage repair, apoptosis and cell cycle regulation (PMID: 29048646, PMID: 32165637). SSRP1 overexpression has been observed in glioma, where it may correlate with stage (PMID: 29048646), and in breast cancer (PMID: 28496363) and hepatocellular carcinoma (PMID: 26755331). | ||||||||||
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