ZFP36L2 - Gene Detail

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Gene Symbol ZFP36L2
Synonyms BRF2 | ERF-2 | ERF2 | OOMD13 | OZEMA13 | RNF162C | TIS11D
Gene Description ZFP36L2, ZFP36 like 2 zinc finger CCCH-type, is an RNA-binding protein and member of the CCCH zinc-finger domain family of proteins involved in regulating cell proliferation, cell cycle (PMID: 29426877), apoptosis (PMID: 17172869), and inflammatory response (PMID: 32655569). Mutations in ZFP36L2 have been identified in acute myeloid leukemia (PMID: 21109922) and overexpression of Zfp36l2 has been observed in pancreatic ductal adenocarcinoma (PMID: 27862697).
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