Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | STK3 | ||||||||||
| Synonyms | KRS1 | MST2 | ||||||||||
| Gene Description | STK3, serine/threonine kinase 3, is a member of the mammalian sterile twenty (MST) kinase family (PMID: 30882881) and is activated by caspases to promote DNA fragmentation during apoptosis (PMID: 29876001) and may play a role in the innate immune response (PMID: 28757478). Stk3 functions as a putative tumor suppressor within the Hippo pathway through YAP1 to regulate cell proliferation (PMID: 15994916, PMID: 24336504, PMID: 29876001), and may also promote tumorigenesis in other tumor types (PMID: 29876001). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
