Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol SVIL
Synonyms MFM10
Gene Description SVIL, supervillin, is a membrane associated actin-binding protein that plays a role in cytoskeletal organization (PMID: 19109420) and cytokinesis (PMID: 24088567), cell migration and motility (PMID: 20331534), and muscle contractility (PMID: 15383618). Elevated SVIL expression has been identified in hepatocellular carcinoma (PMID: 29954442, PMID: 32468064), and a fusion with MAP3K8 has been identified in Spitzoid neoplasms (PMID: 30640733).
Additional content available in CKB BOOST