Gene Detail
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| Gene Symbol | KLF5 | ||||||||||
| Synonyms | BTEB2 | CKLF | IKLF | ||||||||||
| Gene Description | KLF5, Kruppel-like factor 5, is a transcription factor that activates or represses gene transcription, depending on cellular context, thereby, inhibiting or promoting cell survival (PMID: 24323942). Amplification and overexpression of Klf5 has been observed in a variety of tumor types, including intestinal, bladder, gastric, breast (PMID: 28963353), and pancreatic (PMID: 31327760). | ||||||||||
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