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Gene Symbol TRB
Synonyms TCRB | TRB@
Gene Description TRB, T cell receptor beta locus, encodes the T-cell receptor beta chain, which heterodimerizes with T-cell receptor alpha chains to form alpha/beta T-cell receptors that are expressed on T-cells and function in recognition of foreign antigens (PMID: 9143695, PMID: 29055897, PMID: 31994778). TRB fusions are associated with T-cell acute lymphoblastic leukemia (PMID: 36335263, PMID: 33982372, PMID: 16673021).
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