Gene Detail
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| Gene Symbol | VCL | ||||||||||
| Synonyms | CMD1W | CMH15 | HEL114 | MV | MVCL | VINC | ||||||||||
| Gene Description | VCL, vinculin, interacts with F-actin and other cytoskeletal proteins and regulates cell adhesion and migration (PMID: 23466368, PMID: 26195589). VCL-ALK fusions have been identified in pediatric renal cell carcinoma (PMID: 26773439), epithelioid cell histiocytoma (PMID: 25413595), and adult renal cell carcinoma (PMID: 31563285), and a VCL-NTRK2 fusion has been identified in pediatric glioma (PMID: 24705251). | ||||||||||
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