XPO1 - Gene Detail
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| Gene Symbol | XPO1 | ||||||||||||
| Synonyms | CRM-1 | CRM1 | emb | exp1 | ||||||||||||
| Gene Description | XPO1, exportin 1, encodes for an export protein that is responsible for transporting large molecules from the nucleus to the cytoplasm (PMID: 22773955). XPO1 overexpression has been observed in multiple types of cancer including, but not limited to ovarian, pancreatic (PMID: 22209898), diffuse large B-cell lymphoma (PMID: 31949642), colorectal cancer (PMID: 31870117), and multiple myeloma (PMID: 29610030). | ||||||||||||
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