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PAX8 - Gene Detail

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Gene Symbol PAX8
Synonyms PAX-8
Gene Description PAX8, paired-box 8, is a transcription factor, which is involved in the differentiation of multiple cell types including thyroid, kidney, and neural tube (PMID: 23868062). Expression of Pax8 has been associated with several cancer types including thyroid, renal, ovarian (PMID: 30096791, PMID: 31296958), and urothelial carcinoma (PMID: 31932679), while PAX8 fusions have been identified in thyroid cancers (PMID: 23425942, PMID: 31273314).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
7849 2 2q14.1 NM_003466 Unknown
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