Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | MAPKAP1 | ||||||||||
| Synonyms | JC310 | MIP1 | SIN1 | SIN1b | SIN1g | ||||||||||
| Gene Description | MAPKAP1, MAPK associated protein 1, is an mTORC2 complex subunit that acts as a scaffold and functions in substrate recognition (PMID: 37877351) and is involved in regulation of Akt signaling (PMID: 17043309) and cell survival (PMID: 16962653). MAPKAP1 mutations have been identified in ovarian cancer and skin cancer (PMID: 24161930) and overexpression has been identified in a variety of tumor types (PMID: 37877351) including breast cancer (PMID: 27780891), hepatocellular carcinoma (PMID: 23564492), and prostate cancer (PMID: 32088212). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
