PHF23 - Gene Detail
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| Gene Symbol | PHF23 | ||||||||||||
| Synonyms | hJUNE-1b | ||||||||||||
| Gene Description | PHF23, PHD finger protein 23, is a member of the PHD finger protein family (PMID: 41268576) that binds H3K4me3 (PMID: 19430464) and, through epigenetic modification (PMID: 41359382), regulates neurogenesis (PMID: 40447447) and suppresses autophagy (PMID: 25484098). A NUP98-PHF23 fusion has been identified in adult and pediatric acute myeloid leukemia (PMID: 32620764, PMID: 27060678), and increased expression of Phf23 has been observed in non-small cell lung cancer (PMID: 37626047) and glioma (PMID: 41898439). | ||||||||||||
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