Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol NEK11
Synonyms
Gene Description NEK11, NIMA-related kinase 11, is a member of the NEK protein kinase family that negatively regulates CDC25A (PMID: 19734889PMID: 20090422), and plays a putative role in cell cycle regulation in response to DNA damage (PMID: 23132929). Decreased Nek11 expression has been observed in ovarian cancer (PMID: 24969318) and NEK11 mutations have been associated with increased susceptibility to melanoma (PMID: 31704778).
Additional content available in CKB BOOST