Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol RUFY1
Synonyms RABIP4 | ZFYVE12
Gene Description RUFY1, RUN and FYVE domain containing 1, is an effector protein for Rab14 and Rab4, and plays a role in endosomal enlargement and recycling, and interacts with Etk, functioning as a downstream effector (PMID: 20534812, PMID: 11877430). A RUFY1-RET fusion has been identified in MSI-H colorectal cancer (PMID: 30279230).
Additional content available in CKB BOOST