Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol SETD7
Synonyms KMT7 | SET7 | SET7/9 | SET9
Gene Description SETD7, SET domain containing 7, histone lysine methyltransferase, is a histone methyltransferase that regulates chromatin structure to activate and repress gene expression (PMID: 27046831). Setd7 influences a broad variety of targets and pathways with ties to cancer including Tp53, ER, YAP (PMID: 25136132, PMID: 27046831), and breast cancer (PMID: 26779630), and decreased expression has been reported in epithelial tumours (PMID: 31620473).
Additional content available in CKB BOOST