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Gene Symbol TCL1A
Synonyms TCL1
Gene Description TCL1A, TCL1 family AKT coactivator A, is a TCL1 family protooncogene that acts as a co-activator for AKT (PMID: 11707444, PMID: 11839817, PMID: 17360849), interacts with additional proteins to regulate cell signaling (PMID: 30151355), and plays a role in regulation of T- and B-cell development (PMID: 15479728). TCL1A rearrangements are associated with T-cell prolymphocytic leukemia (PMID: 11710897, PMID: 25310835, PMID: 37569479).
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