Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol NPRL3
Synonyms C16orf35 | CGTHBA | FFEVF3 | HS-40 | MARE | NPR3 | RMD11
Gene Description NPRL3, NPR3 like, GATOR1 complex subunit, encodes a protein belonging to the tumor suppressive GATOR complex (PMID: 23723238), that plays a role in the development of the cardiovascular system (PMID: 22538705), and amino acid sensing (PMID: 23723238), and in cortical development in the fetal brain (PMID: 29481864). Decreased expression of NPRL3 has been observed in gastrointestinal stromal tumors (PMID: 31553483).
Additional content available in CKB BOOST