Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol LBH
Synonyms
Gene Description LBH, LBH regulator of WNT signaling pathway, is a transcription co-factor that is regulated by Wnt/beta-catenin signaling and plays a role in mammary epithelial development (PMID: 20606007, PMID: 25655704) and cell cycle regulation (PMID: 28807995). Dysregulation of LBH has been observed in several tumor types (PMID: 37268816), including overexpression in breast cancer (PMID: 20606007) and glioma (PMID: 34739189), and decreased expression in nasopharyngeal carcinoma (PMID: 25557837) and lung adenocarcinoma (PMID: 29788015), and an LBH-ALK fusion has been identified in uterine inflammatory myofibroblastic tumor (PMID: 34522753).
Additional content available in CKB BOOST