ELL - Gene Detail
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| Gene Symbol | ELL | ||||||||||||
| Synonyms | C19orf17 | ELL1 | MEN | PPP1R68 | ||||||||||||
| Gene Description | ELL, elongation factor RNA polymerase II, is a component of the super elongation complex that increases the catalytic rate of RNA polymerase II (PMID: 10995463). A KMT2A ELL fusion has been demonstrated to transform primary myeloid progenitor cells, which eventually leads to acute myeloid leukemia in mouse models (PMID: 10995463). | ||||||||||||
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