Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol NUAK2
Synonyms ANPH2 | SNARK
Gene Description NUAK2, NUAK family kinase 2, is an AMPK family member that plays a role in cytoskeletal and cell cycle regulation (PMID: 21911917, PMID: 25832654) and regulates YAP/TAZ of the Hippo pathway (PMID: 30158528). NUAK2 amplification is associated with acral melanoma (PMID: 21911917, PMID: 25832654) and overexpression has been observed in high-grade bladder cancer (PMID: 30158528) and gastric cancer (PMID: 28352350).
Additional content available in CKB BOOST