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Gene Symbol KDM5C
Synonyms DXS1272E | JARID1C | MRX13 | MRXJ | MRXSCJ | MRXSJ | SMCX | XE169
Gene Description KDM5C, lysine demethylase 5C, is a histone demethylase, regulating gene transcription through chromatin remodeling to regulate cell growth and differentiation (PMID: 25016185). Overexpression of Kdm5c has been reported in prostate cancer (PMID: 25016185, PMID: 30921702) and mutations have been observed in clear cell renal cell carcinoma and pancreatic cancer (PMID: 31221981).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
8242 X Xp11.22 NM_004187 Tumor suppressor (PMID: 30606230)
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