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Gene Detail

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Gene Symbol H3C3
Synonyms H3.1 | H3/c | H3C1 | H3C10 | H3C11 | H3C12 | H3C2 | H3C4 | H3C6 | H3C7 | H3C8 | H3FC | HIST1H3C
Gene Description H3C3, H3 clustered histone 3, encodes a member of the histone H3 family, and plays a role in nucleosome assembly, and cell division (PMID: 25288118, PMID: 14718166, PMID: 11420717). Mutations in H3c3 have been identified in high-grade astrocytoma (PMID: 24705250), and methylation of H3C3 is associated with reduced survival in neuroblastoma patients (PMID: 23034519).
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