Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol ARMC10
Synonyms PNAS-112 | PNAS112 | PSEC0198 | SVH
Gene Description ARMC10, armadillo repeat containting 10, directly decreases the transcriptional activity of Tp53 via binding to the DNA binding domain (PMID: 17904127) and mediates mitochondrial dynamics by serving as a substrate for AMP-activated protein kinase (AMPK) (PMID: 30631047). ARMC10 fusions with BRAF have been observed in lung cancer (PMID: 26314551) and melanoma (PMID: 30254212, PMID: 27864876).
Additional content available in CKB BOOST