SPRTN - Gene Detail
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| Gene Symbol | SPRTN | ||||||||||||
| Synonyms | C1orf124 | DVC1 | PRO4323 | spartan | ||||||||||||
| Gene Description | SPRTN, SprT-like N-terminal domain, is a DNA-dependent protease required for resolution of DNA-protein crosslinks (PMID: 27852435, PMID: 39730693) that plays a role in genome stability (PMID: 25501849, PMID: 32853547, PMID: 34879279). Mutations in SPRTN have been identified in hepatocellular carcinoma (PMID: 25261934, PMID: 38086993). | ||||||||||||
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