Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | ABRAXAS1 | ||||||||||
| Synonyms | ABRA1 | CCDC98 | FAM175A | ||||||||||
| Gene Description | ABRAXAS1 (FAM175A), abraxas 1, BRCA1 A complex subunit, is a BRCA1-binding protein that plays a role in DNA repair and regulation of the G2/M cell cycle phase checkpoint (PMID: 17525340, PMID: 29497033). ABRAXAS1 variants have been identified in several breast cancer pedigrees (PMID: 22357538) and contribute to a small proportion of unexplained hereditary breast cancer cases (PMID: 27270457). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
