RECK - Gene Detail
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| Gene Symbol | RECK | ||||||||||||
| Synonyms | ST15 | ||||||||||||
| Gene Description | RECK, reversion inducing cysteine rich protein with kazal motifs, encodes a membrane-bound glycoprotein involved in tissue homeostasis through negative regulation of matrix metalloproteinases (PMID: 25075007, PMID: 33781845), and also plays a role in Beta-catenin signaling (PMID: 26459448), migration (PMID: 29874120, PMID: 26459448), angiogenesis (PMID: 11747814), and stem cell differentiation (PMID: 26459448). Downregulation of Reck has been observed in various tumor types (PMID: 17828469), including gastric cancer (PMID: 37904179) and melanoma (PMID: 24335752). | ||||||||||||
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