CUL3 - Gene Detail
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| Gene Symbol | CUL3 | ||||||||||||
| Synonyms | CUL-3 | NEDAUS | PHA2E | ||||||||||||
| Gene Description | CUL3, cullin 3, acts as a scaffold in Cullin-RING E3 ubiquitin ligase complexes, and is involved in cell differentiation and vesicle trafficking (PMID: 29249570). Loss of CUL3 has been identified in esophageal squamous cell carcinoma (PMID: 28860350), and overexpression has been demonstrated in breast cancer (PMID: 22825334). | ||||||||||||
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