Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene Symbol | CAT | ||||||||||
Synonyms | |||||||||||
Gene Description | CAT, catalase, is an antioxidant enzyme that prevents oxidative damage to cells by degrading hydrogen peroxide and is involved in the regulation of several cellular processes such as apoptosis, proliferation, and migration (PMID: 26117330, PMID: 12468545, PMID: 18485895). Decreased expression of CAT has been observed in squamous cell carcinoma (PMID: 12413611) and colon carcinoma (PMID: 10357777) while increased activity of CAT has been observed in chronic lymphocytic leukemia (PMID: 20658731). | ||||||||||
|