Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol CDC42BPA
Synonyms MRCK | MRCKA | MRCKalpha | PK428
Gene Description CDC42BPA, CDC42 binding protein kinase alpha, is a serine/threonine kinase that functions downstream of Cdc42, thus regulating cytoskeleton organization and cell motility (PMID: 15723050). Elevated Cdc42bpa expression has been identified in high-grade serous ovarian carcinoma (PMID: 32071169) and has been correlated with metastasis and poor survival in colon cancer patients (PMID: 29072916).
Additional content available in CKB BOOST