Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol ATAD1
Synonyms AFDC1 | FNP001 | hATAD1 | HKPX4 | Msp1 | THORASE
Gene Description ATAD1, ATPase family AAA domain containing 1, is an ATPase that functions in the extraction of mislocalized tail-anchored proteins from the outer mitochondrial membrane as part of the quality control mechanism (PMID: 24843043, PMID: 32886535), and in regulation of synaptic membrane receptor expression (PMID: 21496646). An FGFR2-ATAD1 fusion has been identified in medullary thyroid carcinoma (PMID: 38127829) and ATAD1 is frequently co-deleted with PTEN in prostate adenocarcinoma (PMID: 36409067).
Additional content available in CKB BOOST