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Gene Symbol CCNC
Synonyms CycC | hSRB11 | SRB11
Gene Description CCNC, cyclin C, forms a mediator complex with Ckd8 to mediate transcription of RNA polymerase II-dependent genes (PMID: 28357211, PMID: 22035865, PMID: 30585107). CCNC amplification and overexpression have been observed in breast cancer (PMID: 26452386) and CCNC gene deletion has been reported in T-cell acute lymphoblastic leukemia (PMID: 25344755).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
892 6 6q16.2 NM_005190 Tumor suppressor (PMID: 30606230)
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