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Gene Symbol PHOX2B
Synonyms CCHS | NBLST2 | NBPhox | PMX2B
Gene Description PHOX2B, paired-like homeobox 2b, is a neuronal-specific transcription factor that regulates brain development and patterning (PMID: 12100889). PHOX2B mutations have been identified in neuroblastoma (PMID: 15516980, PMID: 16084642).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
8929 4 4p13 NM_003924 Tumor suppressor (PMID: 30606230)
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