Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | CCNE1 | ||||||||||
| Synonyms | CCNE | pCCNE1 | ||||||||||
| Gene Description | CCNE1, cyclin E1, predominately interacts with CDK2 to regulate the cell-cycle in transition from G1 to S phase (PMID: 14965268, PMID: 27461360). Amplification and/or overexpression of CCNE1 is common in chemoresistant ovarian high grade serous carcinomas (PMID: 27461360, PMID: 32044108), and in general, is associated with poor prognosis in solid tumor types (PMID: 30026836). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
