Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene Symbol | CD1A | ||||||||||
Synonyms | CD1 | FCB6 | HTA1 | R4 | T6 | ||||||||||
Gene Description | CD1a, CD1a molecule, is a member of the CD1 family of transmembrane glycoproteins that play a role in lipid antigen presentation to T-cells involved in mediation of the adaptive immune response (PMID: 11231314, PMID: 28386696). Reduced infiltration of CD1A-expressing dendritic cells has been reported in breast cancer (PMID: 11870535), and decreased CD1A expression has been observed in relapsed/refractory T-cell acute lymphoblastic leukemia (PMID: 33002130). | ||||||||||
|