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Gene Symbol CREB3L1
Synonyms C16DELp11.2 | DEL16p11.2 | OASIS | OI16
Gene Description CREB3L1, cAMP responsive element binding protein 3 like 1, is one of five members of the CREB3 family of transcription factors and is predominately expressed in osteoblasts and plays a role in bone development (PMID: 31334233). A FUS-CREB3L1 fusion has been identified in low-grade fibromyxoid sarcoma (PMID: 15640831, PMID: 31949672) and a EWSR1-CREB3L1 has been identified in small cell osteosarcoma (PMID: 21987447), sclerosing epithelioid fibrosarcoma (PMID: 24441665), and low-grade fibromyxoid sarcoma (PMID: 23588368).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
90993 11 11p11.2 NM_052854 Tumor suppressor (PMID: 30606230)
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