Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | LATS1 | ||||||||||
| Synonyms | WARTS | wts | ||||||||||
| Gene Description | LATS1, large tumor suppressor kinase 1, is a serine/threonine-protein kinase that negatively regulates YAP1 in the Hippo signaling pathway, which plays a role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (PMID: 24026096). LATS1 may play a role as a tumor suppressor in human cancer (PMID: 24026096, PMID: 28644436). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
