INA: Gene Detail - Cancer Knowledgebase (CKB)

To all our CKB CORE users, don’t miss the latest new features now available! Register for a free CORE account here and then login for access. Feel free to contact us at ckbsupport@genomenon.com if you have any questions!

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol

INA

Synonyms

NEF5 | NF-66 | NF66 | TXBP-1

Gene Description

INA, internexin neuronal intermediate filament protein alpha, also known as alpha-internexin is a type IV intermediate filament protein of the cytoskeleton that may play a role in cell differentiation (PMID: 29940892). Altered expression of Ina has been reported in medulloblastomas, neuroblastomas, while loss of expression has been observed in gastroenteropancreatic neuroendocrine neoplasms (PMID: 29940892), and an FGFR2-INA fusion has been reported in low-grade mixed neuronal-glial tumors (PMID: 29767381) and intrahepatic cholangiocarcinoma (PMID: 31109923).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
9118	10	10q24.33	NM_032727	Unknown

Additional content available in

CKB BOOST

Gene Variants 6
Category Variants 2
Molecular Profiles 5
Evidence 9
Clinical Trials 0

KEY FEATURES

CKB CORE^TM

CKB BOOST^TM

CKB FLEX^TM

Access 50 genes & related content

Access 2000+ genes & related content

Scalable & flexible content integration for 2000+ genes

Genes

(50 Genes)

(2000+ Genes)

Gene Variants

Therapies

Limited

Global Drug Approvals

Drug Classes

Limited

Clinical Trials

Limited

Efficacy Evidence

Variant Tier Coding
(AMP/CAP/ASCO)

Advanced Search Capability

System Integration

More about our plans

The public access version, CKB CORE™, encompasses 50 cancer-related genes, and every quarter, a select group of genes are exchanged, focusing on a specific theme. Users can search CKB CORE™ via gene and gene variants. The web-based, subscription version, CKB BOOST™, includes more than 2000 cancer-related genes and is designed to interrogate the knowledgebase for specific data attributes while enabling a robust browse-like feature when the desired content is unknown.

Downloadable data from CKB is available using the FLEX version. CKB FLEX delivers CKB content as a flat file or JSON, enabling CKB data integration.

INA - Gene Detail

Contact