Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol MAP3K13
Synonyms LZK | MEKK13 | MLK
Gene Description MAP3K13, mitogen-activated protein kinase kinase kinase 13, is a member of the mixed lineage kinase (MLK) protein family that is involved in JNK pathway signaling (PMID: 11726277). MAP3K13 mutations have been identified in breast cancer (PMID: 22722201) and amplification has been observed in head and neck squamous cell carcinoma (PMID: 28760853).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
9175 3 3q27.2 NM_004721 Both: Oncogene and Tumor suppressor (PMID: 30606230)
Additional content available in CKB BOOST