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Gene Symbol | CD4 | ||||||||||
Synonyms | CD4mut | IMD79 | Leu-3 | OKT4D | T4 | ||||||||||
Gene Description | CD4, CD4 molecule, is a glycoprotein that recognizes MHC class II peptides on antigen-presenting cells, regulates activation of T-lymphocytes leading to proliferation and differentiation of effector T-cells, and plays a key role in adaptive immune response (PMID: 22474485, PMID: 8057386). CD4 expression is associated with poor survival in acute myeloid leukemia patients (PMID: 9436919). | ||||||||||
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