Gene Detail
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| Gene Symbol | AURKB | ||||||||||
| Synonyms | AIK2 | AIM-1 | AIM1 | ARK-2 | ARK2 | AurB | aurkb-sv1 | aurkb-sv2 | IPL1 | PPP1R48 | STK-1 | STK12 | STK5 | ||||||||||
| Gene Description | AURKB, aurora B kinase, is a serine-threonine protein kinase, which plays a role in the separation of daughter chromatids during cell division and functions in regulation of genomic stability (PMID: 28095398). Overexpression of Aurkb has been associated with poor prognosis in solid tumors, such as non-small cell lung cancer (PMID: 28095398), and in leukemia (PMID: 22940834, PMID: 26199132). | ||||||||||
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