Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol CD7
Synonyms GP40 | LEU-9 | Tp40 | TP41
Gene Description CD7, CD7 molecule, is a glycoprotein receptor found on T cells and NK cells (PMID: 7506726, PMID: 12594257), which plays a role in galectin-1-mediated apoptosis of T-cells (PMID: 10946254, PMID: 18355446) and regulation of cell adhesion through activation of the PI3K pathway (PMID: 11485208, PMID: 9218614). Expression of CD7 has been associated with acute myeloid leukemia (PMID: 9692390, PMID: 33603989), and is a target for immunotherapy (PMID: 37215124).
Additional content available in CKB BOOST