Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol TPTE2
Synonyms TPIP
Gene Description TPTE2, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2, is a member of the PTEN family and results in multiple alternative isoforms, including an isoform that results in phosphatase activity similar to Pten, thereby potentially acting as a tumor suppressor (PMID: 11716755, PMID: 22164291). Loss of TPTE2 has been identified in estrogen-receptor positive breast cancer (PMID: 23826350).
Additional content available in CKB BOOST