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Gene Symbol CD33
Synonyms CD33rSiglec | p67 | SIGLEC-3 | SIGLEC3
Gene Description CD33, CD33 molecule, is a cell adhesion molecule that plays a role in myeloid lineage and may inhibit immune cell activation (PMID: 24991573, PMID: 25320078). Altered expression of Cd33 has been observed in acute myeloid leukemia (PMID: 32150609) and may be a marker for worse prognosis in multiple myeloma (PMID: 24991573), and Cd33 is often expressed on the surface of leukemic stem cells (PMID: 32269970).
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