Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol CD63
Synonyms AD1 | HOP-26 | ME491 | MLA1 | OMA81H | Pltgp40 | TSPAN30
Gene Description CD63, CD63 molecule, encodes a cell surface-associated membrane protein of the tetraspanin family that plays a role in endosomal sorting and cellular protein trafficking, thereby interacting with several different proteins involved in signaling that regulates growth, differentiation, and integrin-dependent cell migration (PMID: 18930046, PMID: 11739647). Increased expression of CD63 has been observed in early stage esophageal cancer (PMID: 28599425), and a fusion with BCAR4 has been identified in lung adenocarcinoma (PMID: 33204025).
Additional content available in CKB BOOST