Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol CD70
Synonyms CD27-L | CD27L | CD27LG | LPFS3 | TNFSF7 | TNLG8A
Gene Description CD70, CD70 molecule, is a cytokine and member of the tumor necrosis factor family that is expressed on activated T cells and B cells (PMID: 29088768). Overexpression of CD70 has been observed in non-small cell lung cancer (PMID: 29088768), HNSCC (PMID: 29496042), and glioblastoma (PMID: 28651374) and in malignant pleural mesothelioma patients with poor prognosis (PMID: 31639216).
Additional content available in CKB BOOST