Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol CD79A
Synonyms IGA | IGAlpha | MB-1 | MB1
Gene Description CD79A, CD79a molecule, is also known as immunoglobulin-associated alpha and encodes for a membrane protein involved in forming the B cell receptor complex, which once formed, induces B cell activation (PMID: 24146823). CD79A mutations demonstrate constitutive activation of the NF-kB pathway in diffuse large B-cell lymphomas (PMID: 21324920, PMID: 30859597).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
973 19 19q13.2 NM_001783 Oncogene (PMID: 30606230)
Additional content available in CKB BOOST