Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol NUAK1
Synonyms ARK5
Gene Description NUAK1, NUAK family kinase 1, encodes an AMPK-related kinase and plays a role in cell survival and the regulation of metabolic homeostasis (PMID: 23873311) and regulates protein phosphatase 1 (PP1) activity to promote spliceosome activity (PMID: 32006464). Elevated expression of NUAK1 has been linked to prognosis in a variety of cancer types including gastric cancer (PMID: 24943992), ovarian cancer (PMID: 27833898), non-small cell lung carcinoma (PMID: 23215946), and nasopharyngeal carcinoma (PMID: 30121842).
Additional content available in CKB BOOST