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Gene Symbol MAFB
Synonyms DURS3 | KRML | MCTO
Gene Description MAFB, MAF bZIP transcription factor B, is a transcription factor that binds to ETS1 to inhibit erythroid differentiation (PMID: 8620536) and plays a role in monocyte development (PMID: 10790365, PMID: 12095145) and beta cell function (PMID: 30425060, PMID: 32488111). IGH-MAFB fusions are associated with adverse prognosis in multiple myeloma (PMID: 32447782, PMID: 16155016, PMID: 32306794).
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